The CDC has stated that while COVID-19 mRNA vaccines are unlikely to pose a risk during pregnancy as they are not a live virus vaccine and do not interact with genetic material DNA, “the potential risks of mRNA vaccines to the pregnant person and her fetus are unknown because these vaccines have not been studied in pregnant women.” CDC, Vaccination Considerations for People who are Pregnant or Breastfeeding (Dec. 15, 2020), available at https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html. Therefore, the CDC recommends that pregnant people be offered the vaccine but that the decision to vaccinate be a personal choice for people who are pregnant and can be discussed with the pregnant person’s care team.
For those who are breastfeeding, the CDC has stated that mRNA vaccines are not thought to be a risk for breastfeeding infants and that those who are breastfeeding may choose to be vaccinated.
For immunocompromised individuals, the CDC has stated that they may receive the vaccine but should be informed that it may not be as effective. CDC, Interim Clinical Considerations for Use of mRNA COVID-19 Vaccines Currently Authorized in the United States, available at https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html